What side effect may indicate digoxin toxicity in a preschool child?

Rubbing of the eyes, in this context, can be associated with digoxin toxicity in preschool children due to its potential impact on vision and neurological symptoms. When digoxin levels become excessively high, children may exhibit signs of visual disturbances, such as blurriness or halos around lights, which can lead to behaviors such as rubbing their eyes as they try to relieve discomfort or clear their vision.

Digoxin has a narrow therapeutic range, making toxicity a concern, especially in young patients with smaller body sizes and fluctuating renal function, which can affect drug clearance. Recognizing unusual behaviors or physical signs such as eye rubbing can prompt further evaluation of digoxin levels and a reassessment of the medication regimen.

It's important to monitor children on digoxin not just for common side effects like changes in heart rate or gastrointestinal symptoms, but also for less obvious signs that may indicate toxicity.